Eine Überprüfung der Methadontabletten zur Schmerzbehandlung

Eine Überprüfung der Methadontabletten zur Schmerzbehandlung

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Keep methadone hydrochloride tablets out of the reach of children. Accidental overdose by a child is a medical emergency and can result hinein death. If a child accidentally takes methadone hydrochloride tablets, get emergency help right away.

Published animal data have reported increased neonatal mortality in the offspring of male rodents that were treated with methadone prior to mating. Hinein these studies, the female rodents were not treated with methadone, indicating paternally-mediated developmental toxicity. Specifically, methadone administered to the male Kollegium prior to mating with methadone-naive females resulted in decreased weight gain hinein progeny after weaning. The male progeny demonstrated reduced thymus weights, whereas the female progeny demonstrated increased adrenal weights. Further, behavioral testing of these male and female progeny revealed significant differences in behavioral tests compared to control animals, suggesting that paternal methadone exposure can produce physiological and behavioral changes hinein progeny hinein this model. Other animal studies have reported that perinatal exposure to opioids including methadone alters neuronal development and behavior rein the offspring. Perinatal methadone exposure in rats has been linked to alterations hinein learning ability, Antrieb activity, thermal regulation, nociceptive responses and sensitivity to drugs.

Stopping methadone hydrochloride tablets. Ask your doctor for instructions on how to stop this medicine slowly to avoid uncomfortable symptoms. You should not stop taking methadone hydrochloride tablets all at once if you have been taking it for more than a few days.

Methadone-maintained patients beginning treatment with these antiretroviral drugs should Beryllium monitored for evidence of withdrawal effects and methadone dose should Beryllium adjusted accordingly.

Particular vigilance is necessary during treatment initiation, during conversion from one opioid to another, and during dose titration.

The use of methadone has not been extensively evaluated in patients with hepatic insufficiency. Methadone is metabolized in the liver and patients with liver impairment may Beryllium at risk of accumulating methadone after multiple dosing.

Fertility – Reproductive function hinein human males may Beryllium decreased by methadone treatment. Reductions hinein ejaculate volume and seminal vesicle and prostate secretions have been reported hinein methadone-treated individuals. In addition, reductions hinein serum testosterone levels and sperm Methadontabletten 10 mg online motility, and abnormalities hinein sperm morphology have been reported. Published animal studies provide additional data indicating that methadone treatment of males can alter reproductive function.

are allergic to methadone or anything else rein methadone hydrochloride tablets. Weiher the end of this leaflet for a complete Streich of ingredients.

There may be new information. This leaflet does not take the place of talking with your doctor about your medical condition or your treatment. Share the important information in this leaflet with members of your household.

Großbrand names for drugs may vary depending on the country you'Response in. Learn how drug names vary and medication tips for travel.

These side effects include slowed breathing and sedation. Magnesiumsilikathydrat to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

Methadone hydrochloride tablets may not be right for you. Before starting methadone hydrochloride tablets, tell your doctor about all your medical and mental conditions including a history of drug or alcohol abuse or addiction.

The respiratory depressant effects of opioids and their capacity to elevate cerebrospinal-fluid pressure may be markedly exaggerated hinein the presence of head injury, other intracranial lesions or a pre-existing increase in intracranial pressure.

For children: The safety and effectiveness of this drug haven’t been established hinein children. It shouldn’t Beryllium used rein children younger than 18 years. Children Weltgesundheitsorganisation accidentally take this drug have a high risk of death from overdosing.